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It can help ease discomfort associated with moderate to severe pain. Tramadol tablets are stronger than standard painkillers like paracetamol and aspirin, however, they are often used with these painkillers to enhance the efficacy or rate of relief.

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Correlations between the 3 data sources were highly linear, with Spearman rho of 0. Drug Saf.

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Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. These pathways are complementary and synergistic, improving tramadol's ability to modulate the perception of and response to pain.

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A year later, German rivals came up with a different explanation for the unusual plant.

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Management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Not for use as an as-needed prn analgesic.

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