Premarin
Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble. It also presents a large number of unidentified molecules with weak estrogenic activity as well as non-human molecules when it is obtained from pregnant mares urine. |
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There is an increased risk of endometrial cancer in a woman with a uterus who uses unopposed estrogens. The Women's Health Initiative WHI estrogen-alone substudy reported increased risks of stroke and deep vein thrombosis DVT in postmenopausal women 50 to 79 years of age during 7. |
Administration of HRT should generally be avoided in women 65 years of age and older, and HRT should not be used to prevent or treat dementia or preserve cognition memory. |
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It's used to help treat symptoms of menopause like hot flashes and vaginal dryness. After menopause, Premarin also helps to prevent osteoporosis. |
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Premarin tablets contain conjugated estrogens, a mixture of estrogen hormones. Estrogen is a female sex hormone produced by the ovaries. |
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Estrogens act through binding to nuclear receptors in estrogen-responsive tissues. |